4F7B

Structure of the lysosomal domain of limp-2

4F7B の概要

• エントリーDOI: 10.2210/pdb4f7b/pdb
• 分子名称: Lysosome membrane protein 2, DI(HYDROXYETHYL)ETHER, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• 機能のキーワード: structural genomics, structural genomics consortium, sgc, scavenger receptor, lipid transport, endocytosis, atherosclerosis, lipoprotein, cell adhesion
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Lysosome membrane; Multi-pass membrane protein: Q14108
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 312713.52

構造登録者

Neculai, D.,Ravichandran, M.,Seitova, A.,Neculai, M.,Pizzaro, J.C.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,Dhe-Paganon, D.,Structural Genomics Consortium (SGC) (登録日: 2012-05-15, 公開日: 2013-10-09, 最終更新日: 2020-07-29)

• 主引用文献: Neculai, D.,Schwake, M.,Ravichandran, M.,Zunke, F.,Collins, R.F.,Peters, J.,Neculai, M.,Plumb, J.,Loppnau, P.,Pizarro, J.C.,Seitova, A.,Trimble, W.S.,Saftig, P.,Grinstein, S.,Dhe-Paganon, S.; Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36.; Nature, 504:172-176, 2013; PubMed: 24162852; DOI: 10.1038/nature12684

実験手法

X-RAY DIFFRACTION (3 Å)