4F76

Crystal Structure of the active HIV-1 Protease in Complex with the products of p1-p6 substrate

4F76 の概要

• エントリーDOI: 10.2210/pdb4f76/pdb
• 関連するPDBエントリー: 4F73 4F74 4F75
• 分子名称: Protease, N terminal product of substrate p1-p6, C terminal product of substrate p1-p6, ... (4 entities in total)
• 機能のキーワード: hiv-1 protease, substrate complex, aids, product complex, aspartyl protease, hydrolase, hydrolase-hydrolase product complex, hydrolase/hydrolase product
• 由来する生物種: HIV-1 M:B_ARV2/SF2 (HIV-1); 詳細
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 22794.87

構造登録者

Schiffer, C.A.,Nalam, M.N.L.,Mittal, S. (登録日: 2012-05-15, 公開日: 2013-05-15, 最終更新日: 2024-02-28)

• 主引用文献: Mittal, S.,Nalam, M.N.L.,Schiffer, C.A.; Crystal Structure of the active HIV-1 Protease in Complex with the products of p1-p6 substrate; To be Published,

実験手法

X-RAY DIFFRACTION (1.85 Å)