4F58

Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient

Summary for 4F58

• Entry DOI: 10.2210/pdb4f58/pdb
• Related: 4F57
• Descriptor: Light chain of Fab of a neutralizing antibody L3, Heavy chain of Fab of a neutralizing antibody L3, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ig, antibody, gp120, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 189222.18

Authors

Pan, R.M.,Kong, X.P. (deposition date: 2012-05-12, release date: 2013-03-27, Last modification date: 2023-09-13)

• Primary citation: Murphy, M.K.,Yue, L.,Pan, R.,Boliar, S.,Sethi, A.,Tian, J.,Pfafferot, K.,Karita, E.,Allen, S.A.,Cormier, E.,Goepfert, P.A.,Borrow, P.,Robinson, J.E.,Gnanakaran, S.,Hunter, E.,Kong, X.P.,Derdeyn, C.A.; Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.; Plos Pathog., 9:e1003173-e1003173, 2013; PubMed: 23468623; DOI: 10.1371/journal.ppat.1003173

Experimental method

X-RAY DIFFRACTION (2.488 Å)