4F4C

The Crystal Structure of the Multi-Drug Transporter

4F4C の概要

• エントリーDOI: 10.2210/pdb4f4c/pdb
• 分子名称: Multidrug resistance protein pgp-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside (3 entities in total)
• 機能のキーワード: abc transporter, atpase, multi-drug transporter, exporter, atp binding, hydrolase, protein transport
• 由来する生物種: Caenorhabditis elegans (nematode)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 146991.33

構造登録者

Jin, M.S.,Oldham, M.L.,Zhang, Q.,Chen, J. (登録日: 2012-05-10, 公開日: 2012-09-26, 最終更新日: 2023-09-13)

• 主引用文献: Jin, M.S.,Oldham, M.L.,Zhang, Q.,Chen, J.; Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.; Nature, 490:566-569, 2012; PubMed: 23000902; DOI: 10.1038/nature11448

実験手法

X-RAY DIFFRACTION (3.4 Å)