4F45
Crystal structure of human CD38 E226Q mutant in complex with NAADP
Summary for 4F45
Entry DOI | 10.2210/pdb4f45/pdb |
Related | 4F46 |
Descriptor | ADP-ribosyl cyclase 1, [[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(3-carboxypyridin-1-ium-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphate (3 entities in total) |
Functional Keywords | cd38, adp-ribosyl cyclase, naadp, calcium signaling, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 2 |
Total formula weight | 61112.29 |
Authors | |
Primary citation | Zhang, H.,Graeff, R.,Lee, H.C.,Hao, Q. Crystal Structures of Human CD38 in Complex with NAADP and ADPRP MESSENGER, 2:44-53, 2013 |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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