4F3J

Crystal Structure of Trimeric gC1q Domain of Human C1QTNF5 associated with Late-onset Retinal Macular Degeneration

4F3J の概要

• エントリーDOI: 10.2210/pdb4f3j/pdb
• 分子名称: Complement C1q tumor necrosis factor-related protein 5 (2 entities in total)
• 機能のキーワード: late-onset retinal macular degeneration, l-ormd, l-ord, amd, age-related macular degeneration, c1qtnf5, ctrp5, s163r, ser163arg, drusen, retinal deposites, 10-strand jelly-roll fold, mfrp, rpe, ciliary body, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted (Probable): Q9BXJ0
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16424.30

構造登録者

Tu, X.,Palczewski, K. (登録日: 2012-05-09, 公開日: 2012-11-07, 最終更新日: 2024-02-28)

• 主引用文献: Tu, X.,Palczewski, K.; Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration.; J.Struct.Biol., 180:439-446, 2012; PubMed: 22892318; DOI: 10.1016/j.jsb.2012.07.011

実験手法

X-RAY DIFFRACTION (1.337 Å)