4F2X

Structure of 3'-Fluoro Cyclohexenyl Nucleic Acid Heptamer

Summary for 4F2X

• Entry DOI: 10.2210/pdb4f2x/pdb
• Related: 4F2Y
• Descriptor: 5'-D(*GP*CP*GP*(XTF)P*GP*CP*G)-3', 5'-D(*CP*GP*CP*AP*CP*GP*C)-3', COBALT HEXAMMINE(III), ... (5 entities in total)
• Functional Keywords: fluoro cyclohexenyl nucleic acid, f-cena, modified dna, b-form dna, dna
• Total number of polymer chains: 4
• Total formula weight: 9207.51

Authors

Pallan, P.S.,Egli, M. (deposition date: 2012-05-08, release date: 2012-05-30, Last modification date: 2023-09-13)

• Primary citation: Seth, P.P.,Yu, J.,Jazayeri, A.,Pallan, P.S.,Allerson, C.R.,Ostergaard, M.E.,Liu, F.,Herdewijn, P.,Egli, M.,Swayze, E.E.; Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2'-Fluoro RNA.; J.Org.Chem., 77:5074-5085, 2012; PubMed: 22591005; DOI: 10.1021/jo300594b

Experimental method

X-RAY DIFFRACTION (1.57 Å)