4F2U
Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus
Summary for 4F2U
Entry DOI | 10.2210/pdb4f2u/pdb |
Related | 3V16 3V18 3V1H 4F2B 4F2T |
Descriptor | 1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, ... (4 entities in total) |
Functional Keywords | alpha beta barrel, phosphatidylinositol-specific phospholipase c, membrane interface, lyase |
Biological source | Staphylococcus aureus subsp. aureus |
Cellular location | Secreted: P45723 |
Total number of polymer chains | 1 |
Total formula weight | 35888.91 |
Authors | Cheng, J.,Goldstein, R.,Stec, B.,Gershenson, A.,Roberts, M.F. (deposition date: 2012-05-08, release date: 2012-12-12, Last modification date: 2023-09-13) |
Primary citation | Cheng, J.,Goldstein, R.,Stec, B.,Gershenson, A.,Roberts, M.F. Competition between Anion Binding and Dimerization Modulates Staphylococcus aureus Phosphatidylinositol-specific Phospholipase C Enzymatic Activity. J.Biol.Chem., 287:40317-40327, 2012 Cited by PubMed: 23038258DOI: 10.1074/jbc.M112.395277 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
Download full validation report