4F2M

Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10

4F2M の概要

• エントリーDOI: 10.2210/pdb4f2m/pdb
• 関連するPDBエントリー: 4F5C
• 分子名称: monoclonal antibody 1AF10, heavy chain, monoclonal antibody 1AF10, light chain, Spike protein, ... (7 entities in total)
• 機能のキーワード: beta-barrel, immunoglobulin, virus entry, virus neutralization, cellular receptor, aminopeptidase n, glycosylation, virus membrane, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 142677.27

構造登録者

Reguera, J.,Santiago, C.,Mudgal, G.,Ordono, D.,Enjuanes, L.,Casasnovas, J.M. (登録日: 2012-05-08, 公開日: 2012-08-22, 最終更新日: 2020-07-29)

• 主引用文献: Reguera, J.,Santiago, C.,Mudgal, G.,Ordono, D.,Enjuanes, L.,Casasnovas, J.M.; Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.; Plos Pathog., 8:e1002859-e1002859, 2012; PubMed: 22876187; DOI: 10.1371/journal.ppat.1002859

実験手法

X-RAY DIFFRACTION (3 Å)