4F21

Crystal structure of carboxylesterase/phospholipase family protein from Francisella tularensis

4F21 の概要

• エントリーDOI: 10.2210/pdb4f21/pdb
• 分子名称: Carboxylesterase/phospholipase family protein, N-((1R,2S)-2-allyl-4-oxocyclobutyl)-4-methylbenzenesulfonamide, bound form (3 entities in total)
• 機能のキーワード: structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, carboxylesterase, phospholipase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Francisella tularensis subsp. tularensis
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 219795.92

構造登録者

Filippova, E.V.,Minasov, G.,Kuhn, M.,Wawrzak, Z.,Shuvalova, L.,Dubrovska, I.,Winsor, J.R.,Kiryukhina, O.,Becker, D.P.,Armoush, N.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2012-05-07, 公開日: 2012-08-29, 最終更新日: 2023-09-13)

• 主引用文献: Filippova, E.V.,Weston, L.A.,Kuhn, M.L.,Geissler, B.,Gehring, A.M.,Armoush, N.,Adkins, C.T.,Minasov, G.,Dubrovska, I.,Shuvalova, L.,Winsor, J.R.,Lavis, L.D.,Satchell, K.J.,Becker, D.P.,Anderson, W.F.,Johnson, R.J.; Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.; J.Biol.Chem., 288:10522-10535, 2013; PubMed: 23430251; DOI: 10.1074/jbc.M112.446625

実験手法

X-RAY DIFFRACTION (2.5 Å)