4EZA

Crystal structure of the atypical phosphoinositide (aPI) binding domain of IQGAP2

4EZA の概要

• エントリーDOI: 10.2210/pdb4eza/pdb
• 分子名称: Ras GTPase-activating-like protein IQGAP2 (2 entities in total)
• 機能のキーワード: gap, structural genomics consortium, sgc, signaling protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26464.69

構造登録者

Van Aalten, D.M.F.,Dixon, M.J.,Gray, A.,Schenning, M.,Agacan, M.,Leslie, N.R.,Downes, C.P.,Batty, I.H.,Nedyalkova, L.,Tempel, W.,Tong, Y.,Zhong, N.,Crombet, L.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (登録日: 2012-05-02, 公開日: 2012-05-16, 最終更新日: 2024-02-28)

• 主引用文献: Dixon, M.J.,Gray, A.,Schenning, M.,Agacan, M.,Tempel, W.,Tong, Y.,Nedyalkova, L.,Park, H.W.,Leslie, N.R.,van Aalten, D.M.,Downes, C.P.,Batty, I.H.; IQGAP Proteins Reveal an Atypical Phosphoinositide (aPI) Binding Domain with a Pseudo C2 Domain Fold.; J.Biol.Chem., 287:22483-22496, 2012; PubMed: 22493426; DOI: 10.1074/jbc.M112.352773

実験手法

X-RAY DIFFRACTION (1.5 Å)