4EWL
Crystal Structure of MshB with glycerol and Acetate bound in the active site
Summary for 4EWL
Entry DOI | 10.2210/pdb4ewl/pdb |
Descriptor | 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... (6 entities in total) |
Functional Keywords | active site, glycerol, acetate, tyrosine 142, histidine 144, mshb, hydrolase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 64708.46 |
Authors | Broadley, S.G.,Sewell, B.T.,Weber, B.W.,Marakalala, M.J.,Steenkamp, D.J. (deposition date: 2012-04-27, release date: 2012-09-26, Last modification date: 2023-09-13) |
Primary citation | Broadley, S.G.,Gumbart, J.C.,Weber, B.W.,Marakalala, M.J.,Steenkamp, D.J.,Sewell, B.T. A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism. Acta Crystallogr.,Sect.D, 68:1450-1459, 2012 Cited by PubMed: 23090394DOI: 10.1107/S090744491203449X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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