4EWL

Crystal Structure of MshB with glycerol and Acetate bound in the active site

4EWL の概要

• エントリーDOI: 10.2210/pdb4ewl/pdb
• 分子名称: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: active site, glycerol, acetate, tyrosine 142, histidine 144, mshb, hydrolase
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 64708.46

構造登録者

Broadley, S.G.,Sewell, B.T.,Weber, B.W.,Marakalala, M.J.,Steenkamp, D.J. (登録日: 2012-04-27, 公開日: 2012-09-26, 最終更新日: 2023-09-13)

• 主引用文献: Broadley, S.G.,Gumbart, J.C.,Weber, B.W.,Marakalala, M.J.,Steenkamp, D.J.,Sewell, B.T.; A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism.; Acta Crystallogr.,Sect.D, 68:1450-1459, 2012; PubMed: 23090394; DOI: 10.1107/S090744491203449X

実験手法

X-RAY DIFFRACTION (1.85 Å)