4ETG

Crystal Structure of MIF L46G mutant

Summary for 4ETG

• Entry DOI: 10.2210/pdb4etg/pdb
• Related: 4EUI 4EVG
• Descriptor: Macrophage migration inhibitory factor, SULFATE ION (3 entities in total)
• Functional Keywords: keto-enol tautomerase, isomerase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P14174
• Total number of polymer chains: 3
• Total formula weight: 37185.04

Authors

Ashrafi, A.,Pojer, F.,Lashuel, H. (deposition date: 2012-04-24, release date: 2012-10-03, Last modification date: 2023-09-13)

• Primary citation: El-Turk, F.,Fauvet, B.,Ashrafi, A.,Ouertatani-Sakouhi, H.,Cho, M.K.,Neri, M.,Cascella, M.,Rothlisberger, U.,Pojer, F.,Zweckstetter, M.,Lashuel, H.; Characterization of molecular determinants of the conformational stability of macrophage migration inhibitory factor: leucine 46 hydrophobic pocket.; Plos One, 7:e45024-e45024, 2012; PubMed: 23028743; DOI: 10.1371/journal.pone.0045024

Experimental method

X-RAY DIFFRACTION (1.61 Å)