4ESX
Crystal structure of C. albicans Thi5 complexed with PLP
Summary for 4ESX
| Entry DOI | 10.2210/pdb4esx/pdb |
| Related | 4ESW |
| Descriptor | Pyrimidine biosynthesis enzyme THI13 (2 entities in total) |
| Functional Keywords | thiamin pyrimidine biosynthesis, transferase |
| Biological source | Candida albicans (yeast) |
| Total number of polymer chains | 2 |
| Total formula weight | 77868.75 |
| Authors | Huang, S.,Fenwick, M.K.,Zhang, Y.,Lai, R.,Hazra, A.,Rajashankar, K.,Philmus, B.,Kinsland, C.,Sanders, J.,Begley, T.P.,Ealick, S.E. (deposition date: 2012-04-23, release date: 2012-09-19, Last modification date: 2024-04-03) |
| Primary citation | Lai, R.Y.,Huang, S.,Fenwick, M.K.,Hazra, A.,Zhang, Y.,Rajashankar, K.,Philmus, B.,Kinsland, C.,Sanders, J.M.,Ealick, S.E.,Begley, T.P. Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. J.Am.Chem.Soc., 134:9157-9159, 2012 Cited by PubMed: 22568620DOI: 10.1021/ja302474a PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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