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4ERZ

X-ray structure of WDR5-MLL4 Win motif peptide binary complex

Summary for 4ERZ
Entry DOI10.2210/pdb4erz/pdb
Related4ERQ 4ERY 4ES0 4ESG
DescriptorWD repeat-containing protein 5, Histone-lysine N-methyltransferase MLL4 (3 entities in total)
Functional Keywordswd40, win motif, beta propeller, 3-10 helix, mll4, lysine methyltransferase, rbbp5, mll1, ash2l, core complex, histone, transcription-transferase complex, transcription/transferase
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus : P61964 Q9UMN6
Total number of polymer chains6
Total formula weight107621.10
Authors
Dharmarajan, V.,Lee, J.-H.,Patel, A.,Skalnik, D.G.,Cosgrove, M.S. (deposition date: 2012-04-21, release date: 2012-05-30, Last modification date: 2024-02-28)
Primary citationDharmarajan, V.,Lee, J.H.,Patel, A.,Skalnik, D.G.,Cosgrove, M.S.
Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287:27275-27289, 2012
Cited by
PubMed: 22665483
DOI: 10.1074/jbc.M112.364125
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

218500

数据于2024-04-17公开中

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