4ERS
A Molecular Basis for Negative Regulation of the Glucagon Receptor
Summary for 4ERS
Entry DOI | 10.2210/pdb4ers/pdb |
Descriptor | Fab light chain, Fab heavy chain, Glucagon receptor, ... (5 entities in total) |
Functional Keywords | glucagon receptor, class-b gpcr, fab, glycosylation, extra-cellular, immune system |
Biological source | Homo sapiens More |
Cellular location | Cell membrane; Multi-pass membrane protein: P47871 |
Total number of polymer chains | 3 |
Total formula weight | 60104.22 |
Authors | Murray, J.M.,Koth, C.M.,Mukund, S. (deposition date: 2012-04-20, release date: 2012-08-29, Last modification date: 2020-07-29) |
Primary citation | Koth, C.M.,Murray, J.M.,Mukund, S.,Madjidi, A.,Minn, A.,Clarke, H.J.,Wong, T.,Chiang, V.,Luis, E.,Estevez, A.,Rondon, J.,Zhang, Y.,Hotzel, I.,Allan, B.B. Molecular basis for negative regulation of the glucagon receptor. Proc.Natl.Acad.Sci.USA, 109:14393-14398, 2012 Cited by PubMed: 22908259DOI: 10.1073/pnas.1206734109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.637 Å) |
Structure validation
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