4EQK

Crystal structure of the cap-binding domain of polymerase basic protein 2 from influenza virus A/Hong Kong/1/68 (h3n2) with bound m7GTP

Summary for 4EQK

• Entry DOI: 10.2210/pdb4eqk/pdb
• Related: 4ENF 4ES5
• Descriptor: Polymerase basic protein 2, NITRATE ION, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: cap binding, transcription
• Biological source: Influenza A virus
• Cellular location: Virion: Q91MB1
• Total number of polymer chains: 1
• Total formula weight: 19904.67

Authors

Meng, G.,Liu, Y.,Zheng, X. (deposition date: 2012-04-19, release date: 2013-03-06, Last modification date: 2023-11-08)

• Primary citation: Liu, Y.,Qin, K.,Meng, G.,Zhang, J.,Zhou, J.,Zhao, G.,Luo, M.,Zheng, X.; Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus; J.Biol.Chem., 288:11013-11023, 2013; PubMed: 23436652; DOI: 10.1074/jbc.M112.392878

Experimental method

X-RAY DIFFRACTION (1.95 Å)