4EQF

Trip8b-1a#206-567 interacting with the carboxy-terminal seven residues of HCN2

4EQF の概要

• エントリーDOI: 10.2210/pdb4eqf/pdb
• 関連するPDBエントリー: 1FCH 3CVP 3CVQ
• 分子名称: PEX5-related protein, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (2 entities in total)
• 機能のキーワード: accessory protein, tetratricopeptide repeat, tpr, accessory protein for hcn channels, hcn, protein binding-transport protein complex, protein binding/transport protein
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm (By similarity): Q8C437; Membrane; Multi-pass membrane protein: O88703
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41746.79

構造登録者

Bankston, J.R.,Camp, S.S.,Dimaio, F.,Lewis, A.S.,Chetkovich, D.M.,Zagotta, W.N. (登録日: 2012-04-18, 公開日: 2012-05-30, 最終更新日: 2023-09-13)

• 主引用文献: Bankston, J.R.,Camp, S.S.,Dimaio, F.,Lewis, A.S.,Chetkovich, D.M.,Zagotta, W.N.; Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels.; Proc.Natl.Acad.Sci.USA, 109:7899-7904, 2012; PubMed: 22550182; DOI: 10.1073/pnas.1201997109

実験手法

X-RAY DIFFRACTION (3 Å)