4EOT

Crystal structure of the MafA homodimer bound to the consensus MARE

4EOT の概要

• エントリーDOI: 10.2210/pdb4eot/pdb
• 分子名称: Transcription factor MafA, 5'-D(*CP*CP*GP*GP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*GP*G)-3', 5'-D(*CP*CP*CP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*CP*CP*G)-3', ... (5 entities in total)
• 機能のキーワード: leucine zipper, transcription factor, dna binding, nucleus, transcription-dna complex, transcription/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q8NHW3
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 34808.16

構造登録者

Lu, X.,Guanga, G.,Wan, C.,Rose, R.B. (登録日: 2012-04-15, 公開日: 2012-11-28, 最終更新日: 2023-09-13)

• 主引用文献: Lu, X.,Guanga, G.P.,Wan, C.,Rose, R.B.; A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities.; Biochemistry, 51:9706-9717, 2012; PubMed: 23148532; DOI: 10.1021/bi301248j

実験手法

X-RAY DIFFRACTION (2.855 Å)