4EHQ

Crystal Structure of Calmodulin Binding Domain of Orai1 in Complex with Ca2+/Calmodulin Displays a Unique Binding Mode

4EHQ の概要

• エントリーDOI: 10.2210/pdb4ehq/pdb
• 分子名称: Calmodulin, Calcium release-activated calcium channel protein 1, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: calmodulin, orai1, calcium dependent inactivation, ef hand, calcium binding, calcium-dependent inactivation, calmodulin binding domain of orai1, none, cytosol, protein binding
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• 細胞内の位置: Cytoplasm, cytoskeleton, spindle: P62161; Cell membrane; Multi-pass membrane protein: Q96D31
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 19619.91

構造登録者

Liu, Y.,Zheng, X.,Mueller, G.A.,Sobhany, M.,DeRose, E.F.,Zhang, Y.,London, R.E.,Birnbaumer, L. (登録日: 2012-04-03, 公開日: 2012-11-07, 最終更新日: 2023-09-13)

• 主引用文献: Liu, Y.,Zheng, X.,Mueller, G.A.,Sobhany, M.,Derose, E.F.,Zhang, Y.,London, R.E.,Birnbaumer, L.; Crystal structure of calmodulin binding domain of orai1 in complex with ca2+*calmodulin displays a unique binding mode.; J.Biol.Chem., 287:43030-43041, 2012; PubMed: 23109337; DOI: 10.1074/jbc.M112.380964

実験手法

X-RAY DIFFRACTION (1.9005 Å)