4EEQ

Crystal structure of E. faecalis DNA ligase with inhibitor

Summary for 4EEQ

• Entry DOI: 10.2210/pdb4eeq/pdb
• Related: 4EFB 4EFE
• Descriptor: DNA ligase, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ... (5 entities in total)
• Functional Keywords: alfa-betta protein, adenylation, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• Biological source: Enterococcus faecalis
• Total number of polymer chains: 1
• Total formula weight: 38683.16

Authors

Wang, T.,Charifson, P.,Wei, Y. (deposition date: 2012-03-28, release date: 2013-04-03, Last modification date: 2024-02-28)

• Primary citation: Wang, T.,Charifson, P.,Wei, Y.; Design, Synthesis and Activity Evaluation of Potent NAD+ DNA Ligase Inhibitors as Potential Antibacterial Agents.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)