4ED4

Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP

4ED4 の概要

• エントリーDOI: 10.2210/pdb4ed4/pdb
• 関連するPDBエントリー: 4DXL
• 分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: ssgcid, nih, niaid, sbri, emerald biostructures, structural genomics, seattle structural genomics center for infectious disease, transferase
• 由来する生物種: Mycobacterium abscessus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 33249.76

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-03-26, 公開日: 2012-04-04, 最終更新日: 2023-09-13)

• 主引用文献: Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J.; Increasing the structural coverage of tuberculosis drug targets.; Tuberculosis (Edinb), 95:142-148, 2015; PubMed: 25613812; DOI: 10.1016/j.tube.2014.12.003

実験手法

X-RAY DIFFRACTION (1.75 Å)