4ECL

Crystal structure of the cytoplasmic domain of vancomycin resistance serine racemase VanTg

Summary for 4ECL

Entry DOI	10.2210/pdb4ecl/pdb
Descriptor	Serine racemase, CHLORIDE ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	antibiotic resistance, vancomycin resistance, center for structural genomics of infectious diseases (csgid), alpha/beta barrel, tim barrel, type iii pyridoxal 5-phosphate (plp)-dependent enzyme, acyltransferase family, l-serine racemase, d-serine racemase, isomerase, l-serine, d-serine, plp, pyridoxal 5-phosphate, cytoplasmic
Biological source	Enterococcus faecalis
Total number of polymer chains	4
Total formula weight	167411.39
Authors	Stogios, P.J.,Wawrzak, Z.,Minasov, G.,Evdokimova, E.,Egorova, O.,Cosme, J.,Di Leo, R.,Krishnamoorthy, M.,Meziane-Cherif, D.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-03-26, release date: 2012-04-18, Last modification date: 2016-06-01)
Primary citation	Meziane-Cherif, D.,Stogios, P.J.,Evdokimova, E.,Egorova, O.,Savchenko, A.,Courvalin, P. Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases. MBio, 6:e00806-e00806, 2015 Cited by PubMed: 26265719 DOI: 10.1128/mBio.00806-15 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.017 Å)

Structure validation