4E91
Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BD3
4E91 の概要
エントリーDOI | 10.2210/pdb4e91/pdb |
関連するPDBエントリー | 4E92 |
分子名称 | Gag protein, 4-{2-[5-(3-chlorophenyl)-1H-pyrazol-4-yl]-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazol-5-yl}benzoic acid, (3S)-1-ethyl-3-[3-hydroxy-5-(pyridin-3-yl)phenyl]-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, ... (5 entities in total) |
機能のキーワード | structural protein capsid, structural protein, structural protein-inhibitor complex, structural protein/inhibitor |
由来する生物種 | Human immunodeficiency virus 1 |
細胞内の位置 | Capsid protein p24: Virion (By similarity). Matrix protein p17: Virion (By similarity). Nucleocapsid protein p7: Virion (By similarity): Q79791 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 34480.23 |
構造登録者 | |
主引用文献 | Lemke, C.T.,Titolo, S.,von Schwedler, U.,Goudreau, N.,Mercier, J.F.,Wardrop, E.,Faucher, A.M.,Coulombe, R.,Banik, S.S.,Fader, L.,Gagnon, A.,Kawai, S.H.,Rancourt, J.,Tremblay, M.,Yoakim, C.,Simoneau, B.,Archambault, J.,Sundquist, W.I.,Mason, S.W. Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein. J.Virol., 86:6643-6655, 2012 Cited by PubMed: 22496222DOI: 10.1128/JVI.00493-12 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.7 Å) |
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