4E5I

Crystal structure of avian influenza virus PAn bound to compound 4

Summary for 4E5I

• Entry DOI: 10.2210/pdb4e5i/pdb
• Related: 4E5E 4E5F 4E5G 4E5H 4E5J 4E5L
• Descriptor: Polymerase protein PA, SULFATE ION, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: endonuclease domain, h5n1 subtype, viral protein, transcription
• Biological source: Influenza A virus; More
• Cellular location: Host cytoplasm . Host nucleus : Q5EP34
• Total number of polymer chains: 4
• Total formula weight: 89816.58

Authors

DuBois, R.M.,Slavish, P.J.,Webb, T.R.,White, S.W. (deposition date: 2012-03-14, release date: 2012-08-08, Last modification date: 2023-09-13)

• Primary citation: Dubois, R.M.,Slavish, P.J.,Baughman, B.M.,Yun, M.K.,Bao, J.,Webby, R.J.,Webb, T.R.,White, S.W.; Structural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA Endonuclease.; Plos Pathog., 8:e1002830-e1002830, 2012; PubMed: 22876176; DOI: 10.1371/journal.ppat.1002830

Experimental method

X-RAY DIFFRACTION (2.944 Å)