4E54

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

Summary for 4E54

• Entry DOI: 10.2210/pdb4e54/pdb
• Related: 4E3H
• Descriptor: DNA damage-binding protein 1, DNA damage-binding protein 2, AP24 DNA strand, ... (4 entities in total)
• Functional Keywords: beta barrel, double helix, ddb1:wd40 beta-barrel fold, dna damage, dna repair, host-virus interactions, protein ubiquitination, proteosomal degradation, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: Q16531; Nucleus: Q92466
• Total number of polymer chains: 4
• Total formula weight: 192022.27

Authors

Yeh, J.I.,Du, S. (deposition date: 2012-03-14, release date: 2012-08-08, Last modification date: 2023-09-13)

• Primary citation: Yeh, J.I.,Levine, A.S.,Du, S.,Chinte, U.,Ghodke, H.,Wang, H.,Shi, H.,Hsieh, C.L.,Conway, J.F.,Van Houten, B.,Rapic-Otrin, V.; Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.; Proc.Natl.Acad.Sci.USA, 109:E2737-E2746, 2012; PubMed: 22822215; DOI: 10.1073/pnas.1110067109

Experimental method

X-RAY DIFFRACTION (2.85 Å)