4E2I

The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase

4E2I の概要

• エントリーDOI: 10.2210/pdb4e2i/pdb
• 分子名称: Large T antigen, DNA polymerase alpha subunit B, ZINC ION (3 entities in total)
• 機能のキーワード: replication initiation, hydrolase-dna binding complex, hydrolase-dna binding protein complex, hydrolase/dna binding protein
• 由来する生物種: Simian virus 40 (SV40); 詳細
• 細胞内の位置: Nucleus: Q14181
• タンパク質・核酸の鎖数: 23
• 化学式量合計: 598246.55

構造登録者

Zhou, B.,Arnett, D.R.,Yu, X.,Brewster, A.,Sowd, G.A.,Xie, C.L.,Vila, S.,Gai, D.,Fanning, E.,Chen, X.S. (登録日: 2012-03-08, 公開日: 2012-06-13, 最終更新日: 2024-02-28)

• 主引用文献: Zhou, B.,Arnett, D.R.,Yu, X.,Brewster, A.,Sowd, G.A.,Xie, C.L.,Vila, S.,Gai, D.,Fanning, E.,Chen, X.S.; Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase.; J.Biol.Chem., 287:26854-26866, 2012; PubMed: 22700977; DOI: 10.1074/jbc.M112.363655

実験手法

X-RAY DIFFRACTION (5 Å)