4E1V
X-RAY Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with 5-Fluorouracil at 2.15 A Resolution
Replaces: 3NSRSummary for 4E1V
Entry DOI | 10.2210/pdb4e1v/pdb |
Descriptor | Uridine phosphorylase, 5-FLUOROURACIL, GLYCEROL, ... (6 entities in total) |
Functional Keywords | rossmann fold, drug metabolism, transferase |
Biological source | Salmonella enterica subsp. enterica serovar Typhimurium |
Cellular location | Cytoplasm (By similarity): P0A1F6 |
Total number of polymer chains | 9 |
Total formula weight | 246202.28 |
Authors | Lashkov, A.A.,Sotnichenko, S.E.,Prokofev, I.I.,Gabdoulkhakov, A.G.,Mikhailov, A.M. (deposition date: 2012-03-07, release date: 2013-03-06, Last modification date: 2023-09-13) |
Primary citation | Lashkov, A.A.,Sotnichenko, S.E.,Prokofiev, I.I.,Gabdulkhakov, A.G.,Agapov, I.I.,Shtil, A.A.,Betzel, C.,Mironov, A.S.,Mikhailov, A.M. X-ray structure of Salmonella typhimurium uridine phosphorylase complexed with 5-fluorouracil and molecular modelling of the complex of 5-fluorouracil with uridine phosphorylase from Vibrio cholerae. Acta Crystallogr.,Sect.D, 68:968-974, 2012 Cited by PubMed: 22868762DOI: 10.1107/S090744491201815X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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