4E1V

X-RAY Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with 5-Fluorouracil at 2.15 A Resolution

Replaces:  3NSR

Summary for 4E1V

• Entry DOI: 10.2210/pdb4e1v/pdb
• Descriptor: Uridine phosphorylase, 5-FLUOROURACIL, GLYCEROL, ... (6 entities in total)
• Functional Keywords: rossmann fold, drug metabolism, transferase
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium
• Cellular location: Cytoplasm (By similarity): P0A1F6
• Total number of polymer chains: 9
• Total formula weight: 246202.28

Authors

Lashkov, A.A.,Sotnichenko, S.E.,Prokofev, I.I.,Gabdoulkhakov, A.G.,Mikhailov, A.M. (deposition date: 2012-03-07, release date: 2013-03-06, Last modification date: 2023-09-13)

• Primary citation: Lashkov, A.A.,Sotnichenko, S.E.,Prokofiev, I.I.,Gabdulkhakov, A.G.,Agapov, I.I.,Shtil, A.A.,Betzel, C.,Mironov, A.S.,Mikhailov, A.M.; X-ray structure of Salmonella typhimurium uridine phosphorylase complexed with 5-fluorouracil and molecular modelling of the complex of 5-fluorouracil with uridine phosphorylase from Vibrio cholerae.; Acta Crystallogr.,Sect.D, 68:968-974, 2012; PubMed: 22868762; DOI: 10.1107/S090744491201815X

Experimental method

X-RAY DIFFRACTION (2.15 Å)