4E00
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with ADP
4E00 の概要
エントリーDOI | 10.2210/pdb4e00/pdb |
関連するPDBエントリー | 3TZ0 3TZ2 3TZ4 3TZ5 4DZY 4E01 |
分子名称 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, ADENOSINE-5'-DIPHOSPHATE, 3,6-dichloro-1-benzothiophene-2-carboxylic acid, ... (6 entities in total) |
機能のキーワード | ghkl protein kinase, allosteric kinase inhibitor, branched-chain alpha-ketoacid, branched-chain amino acids, maple syrup urine disease, diabetes and obesity, bergerat nucleotide-binding fold, protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
由来する生物種 | Rattus norvegicus (rat) |
細胞内の位置 | Mitochondrion matrix: Q00972 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 48111.95 |
構造登録者 | Tso, S.C.,Chuang, J.L.,Gui, W.J.,Wynn, R.M.,Li, J.,Chuang, D.T. (登録日: 2012-03-01, 公開日: 2013-03-27, 最終更新日: 2024-02-28) |
主引用文献 | Tso, S.C.,Chuang, J.L.,Gui, W.J.,Wynn, R.M.,Li, J.,Chuang, D.T. Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with ADP To be Published, |
実験手法 | X-RAY DIFFRACTION (2.15 Å) |
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