4DZ3

Crystal structure of a Peptidyl-prolyl cis-trans isomerase with surface mutation M61H from Burkholderia pseudomallei complexed with FK506

4DZ3 の概要

• エントリーDOI: 10.2210/pdb4dz3/pdb
• 関連するPDBエントリー: 2ke0 2ko7 2l2s 3uf8 3uqa 3uqb 3vaw 4DZ2
• 分子名称: Peptidyl-prolyl cis-trans isomerase, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: ssgcid, isomerase, structural genomics, seattle structural genomics center for infectious disease
• 由来する生物種: Burkholderia pseudomallei
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 26164.30

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2012-02-29, 公開日: 2012-03-28, 最終更新日: 2023-09-13)

• 主引用文献: Begley, D.W.,Fox, D.,Jenner, D.,Juli, C.,Pierce, P.G.,Abendroth, J.,Muruthi, M.,Safford, K.,Anderson, V.,Atkins, K.,Barnes, S.R.,Moen, S.O.,Raymond, A.C.,Stacy, R.,Myler, P.J.,Staker, B.L.,Harmer, N.J.,Norville, I.H.,Holzgrabe, U.,Sarkar-Tyson, M.,Edwards, T.E.,Lorimer, D.D.; A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.; Antimicrob.Agents Chemother., 58:1458-1467, 2014; PubMed: 24366729; DOI: 10.1128/AAC.01875-13

実験手法

X-RAY DIFFRACTION (2 Å)