4DY0

Crystal structure of native protease nexin-1 with heparin

4DY0 の概要

• エントリーDOI: 10.2210/pdb4dy0/pdb
• 分子名称: Glia-derived nexin, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: serpin, protease inhibitor, thrombin, cell surface, hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 84994.90

構造登録者

Huntington, J.A.,Li, W. (登録日: 2012-02-28, 公開日: 2012-08-15, 最終更新日: 2024-03-13)

• 主引用文献: Li, W.,Huntington, J.A.; Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism.; Blood, 120:459-467, 2012; PubMed: 22618708; DOI: 10.1182/blood-2012-03-415869

実験手法

X-RAY DIFFRACTION (2.35 Å)