4DUA

cytochrome P450 BM3h-9D7 MRI sensor, no ligand

Summary for 4DUA

• Entry DOI: 10.2210/pdb4dua/pdb
• Related: 4DTW 4DTY 4DTZ 4DU2 4DUB 4DUC 4DUD 4DUE 4DUF
• Descriptor: cytochrome P450 BM3 variant 9D7, PROTOPORPHYRIN IX CONTAINING FE, TRIETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: cytochrome p450, mri contrast sensor, directed evolution, oxidoreductase
• Biological source: Bacillus megaterium
• Cellular location: Cytoplasm : P14779
• Total number of polymer chains: 2
• Total formula weight: 109081.64

Authors

Brustad, E.M.,Lelyveld, V.S.,Snow, C.D.,Crook, N.,Martinez, F.M.,Scholl, T.J.,Jasanoff, A.,Arnold, F.H. (deposition date: 2012-02-21, release date: 2012-06-13, Last modification date: 2023-09-13)

• Primary citation: Brustad, E.M.,Lelyveld, V.S.,Snow, C.D.,Crook, N.,Jung, S.T.,Martinez, F.M.,Scholl, T.J.,Jasanoff, A.,Arnold, F.H.; Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin.; J.Mol.Biol., 422:245-262, 2012; PubMed: 22659321; DOI: 10.1016/j.jmb.2012.05.029

Experimental method

X-RAY DIFFRACTION (2 Å)