4DTC

Crystal Structure of DPP-IV with Compound C5

Summary for 4DTC

• Entry DOI: 10.2210/pdb4dtc/pdb
• Related: 4DSA 4DSZ
• Descriptor: Dipeptidyl peptidase 4, N-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butyl]-3'-(trifluoromethyl)biphenyl-4-carboxamide (2 entities in total)
• Functional Keywords: inhibitor complex, serine exopeptidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Dipeptidyl peptidase 4 soluble form: Secreted. Cell membrane; Single-pass type II membrane protein: P27487
• Total number of polymer chains: 2
• Total formula weight: 169858.07

Authors

Xiong, B.,Zhu, L.R.,Chen, D.Q.,Zhao, Y.L.,Jiang, F.,Shen, J.K. (deposition date: 2012-02-21, release date: 2013-02-27, Last modification date: 2023-11-08)

• Primary citation: Xiong, B.,Zhu, L.R.,Chen, D.Q.,Zhao, Y.L.,Jiang, F.,Shen, J.K.; Crystal Structure of DPP-IV with Compound C5; To be Published,

Experimental method

X-RAY DIFFRACTION (3 Å)