Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4DOS

Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, Bound to DLPC and a Fragment of TIF-2

Summary for 4DOS
Entry DOI10.2210/pdb4dos/pdb
Related4DOR
DescriptorNuclear receptor subfamily 5 group A member 2, Nuclear receptor coactivator 2, PENTAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywordsnuclear receptor, ligand binding domain, phospholipids, nr5a, diabetes, phosphatidylcholine, dlpc, transcription
Biological sourceHomo sapiens (human)
More
Cellular locationNucleus (Probable): O00482
Nucleus: Q15596
Total number of polymer chains3
Total formula weight32669.74
Authors
Musille, P.M.,Ortlund, E.A. (deposition date: 2012-02-10, release date: 2012-04-18, Last modification date: 2024-02-28)
Primary citationMusille, P.M.,Pathak, M.C.,Lauer, J.L.,Hudson, W.H.,Griffin, P.R.,Ortlund, E.A.
Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.
Nat.Struct.Mol.Biol., 19:532-537, 2012
Cited by
PubMed: 22504882
DOI: 10.1038/nsmb.2279
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

건을2024-03-27부터공개중

PDB statisticsPDBj update infoContact PDBjnumon