4DOR

Human Nuclear Receptor Liver Receptor Homologue-1, LRH-1, in its apo State Bound to a Fragment of Human SHP Box1

4DOR の概要

• エントリーDOI: 10.2210/pdb4dor/pdb
• 関連するPDBエントリー: 4DOR
• 分子名称: Nuclear receptor subfamily 5 group A member 2, Nuclear receptor subfamily 0 group B member 2, L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total)
• 機能のキーワード: nuclear receptor, ligand binding domain, phospholipids, nr5a, diabetes, phosphatidylcholine, transcription
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus : O00482 Q15466
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 62529.06

構造登録者

Musille, P.M.,Ortlund, E.A. (登録日: 2012-02-10, 公開日: 2012-04-18, 最終更新日: 2024-02-28)

• 主引用文献: Musille, P.M.,Pathak, M.C.,Lauer, J.L.,Hudson, W.H.,Griffin, P.R.,Ortlund, E.A.; Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.; Nat.Struct.Mol.Biol., 19:532-537, 2012; PubMed: 22504882; DOI: 10.1038/nsmb.2279

実験手法

X-RAY DIFFRACTION (1.9 Å)