4DOM
Crystal Structure of the TIR-domain of Human Myeloid Differentiation Primary Response protein (MyD88)
Summary for 4DOM
Entry DOI | 10.2210/pdb4dom/pdb |
Descriptor | Myeloid differentiation primary response protein MyD88 (2 entities in total) |
Functional Keywords | myd88_human, tir-domain, toll-like receptor, adopter domain, innate immune signaling, tirap/mal, signaling protein, lysine methylation |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 16718.62 |
Authors | Jiang, J.S.,Snyder, G.A.,Xiao, T. (deposition date: 2012-02-09, release date: 2013-04-10, Last modification date: 2023-12-06) |
Primary citation | Snyder, G.A.,Cirl, C.,Jiang, J.,Chen, K.,Waldhuber, A.,Smith, P.,Rommler, F.,Snyder, N.,Fresquez, T.,Durr, S.,Tjandra, N.,Miethke, T.,Xiao, T.S. Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli. Proc.Natl.Acad.Sci.USA, 110:6985-6990, 2013 Cited by PubMed: 23569230DOI: 10.1073/pnas.1215770110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.798 Å) |
Structure validation
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