4DOM

Crystal Structure of the TIR-domain of Human Myeloid Differentiation Primary Response protein (MyD88)

4DOM の概要

• エントリーDOI: 10.2210/pdb4dom/pdb
• 分子名称: Myeloid differentiation primary response protein MyD88 (2 entities in total)
• 機能のキーワード: myd88_human, tir-domain, toll-like receptor, adopter domain, innate immune signaling, tirap/mal, signaling protein, lysine methylation
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16718.62

構造登録者

Jiang, J.S.,Snyder, G.A.,Xiao, T. (登録日: 2012-02-09, 公開日: 2013-04-10, 最終更新日: 2023-12-06)

• 主引用文献: Snyder, G.A.,Cirl, C.,Jiang, J.,Chen, K.,Waldhuber, A.,Smith, P.,Rommler, F.,Snyder, N.,Fresquez, T.,Durr, S.,Tjandra, N.,Miethke, T.,Xiao, T.S.; Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.; Proc.Natl.Acad.Sci.USA, 110:6985-6990, 2013; PubMed: 23569230; DOI: 10.1073/pnas.1215770110

実験手法

X-RAY DIFFRACTION (1.798 Å)