4DOH
IL20/IL201/IL20R2 Ternary Complex
Summary for 4DOH
Entry DOI | 10.2210/pdb4doh/pdb |
Descriptor | Interleukin-20, Interleukin-20 receptor subunit beta, Interleukin-20 receptor subunit alpha, ... (5 entities in total) |
Functional Keywords | il10 family cytokine receptor complex, alpha helical cytokine fold beta sandwhich receptor fold, signaling complex, extracellular, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: Q9NYY1 Membrane; Single-pass type I membrane protein (By similarity): Q6UXL0 Q9UHF4 |
Total number of polymer chains | 6 |
Total formula weight | 132994.55 |
Authors | Logsdon, N.J.,Walter, M.R. (deposition date: 2012-02-09, release date: 2012-07-18, Last modification date: 2020-07-29) |
Primary citation | Logsdon, N.J.,Deshpande, A.,Harris, B.D.,Rajashankar, K.R.,Walter, M.R. Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines. Proc.Natl.Acad.Sci.USA, 109:12704-12709, 2012 Cited by PubMed: 22802649DOI: 10.1073/pnas.1117551109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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