4DOH

IL20/IL201/IL20R2 Ternary Complex

Summary for 4DOH

Entry DOI	10.2210/pdb4doh/pdb
Descriptor	Interleukin-20, Interleukin-20 receptor subunit beta, Interleukin-20 receptor subunit alpha, ... (5 entities in total)
Functional Keywords	il10 family cytokine receptor complex, alpha helical cytokine fold beta sandwhich receptor fold, signaling complex, extracellular, signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Secreted: Q9NYY1 Membrane; Single-pass type I membrane protein (By similarity): Q6UXL0 Q9UHF4
Total number of polymer chains	6
Total formula weight	132994.55
Authors	Logsdon, N.J.,Walter, M.R. (deposition date: 2012-02-09, release date: 2012-07-18, Last modification date: 2020-07-29)
Primary citation	Logsdon, N.J.,Deshpande, A.,Harris, B.D.,Rajashankar, K.R.,Walter, M.R. Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines. Proc.Natl.Acad.Sci.USA, 109:12704-12709, 2012 Cited by PubMed: 22802649 DOI: 10.1073/pnas.1117551109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation