4DOH

IL20/IL201/IL20R2 Ternary Complex

4DOH の概要

• エントリーDOI: 10.2210/pdb4doh/pdb
• 分子名称: Interleukin-20, Interleukin-20 receptor subunit beta, Interleukin-20 receptor subunit alpha, ... (5 entities in total)
• 機能のキーワード: il10 family cytokine receptor complex, alpha helical cytokine fold beta sandwhich receptor fold, signaling complex, extracellular, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: Q9NYY1; Membrane; Single-pass type I membrane protein (By similarity): Q6UXL0 Q9UHF4
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 132994.55

構造登録者

Logsdon, N.J.,Walter, M.R. (登録日: 2012-02-09, 公開日: 2012-07-18, 最終更新日: 2020-07-29)

• 主引用文献: Logsdon, N.J.,Deshpande, A.,Harris, B.D.,Rajashankar, K.R.,Walter, M.R.; Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines.; Proc.Natl.Acad.Sci.USA, 109:12704-12709, 2012; PubMed: 22802649; DOI: 10.1073/pnas.1117551109

実験手法

X-RAY DIFFRACTION (2.8 Å)