4DK4

Crystal Structure of Trypanosoma brucei dUTPase with dUpNp, Ca2+ and Na+

Summary for 4DK4

• Entry DOI: 10.2210/pdb4dk4/pdb
• Related: 4DK2 4DKB 4DL8 4DLC
• Descriptor: Deoxyuridine triphosphatase, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-DIPHOSPHATE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: all alpha ntp pyrophosphohydrolase, all alpha ntp pyrophosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 65389.19

Authors

Hemsworth, G.R.,Gonzalez-Pacanowska, D.,Wilson, K.S. (deposition date: 2012-02-03, release date: 2013-08-07, Last modification date: 2023-09-13)

• Primary citation: Hemsworth, G.R.,Gonzalez-Pacanowska, D.,Wilson, K.S.; On the catalytic mechanism of dimeric dUTPases.; Biochem.J., 456:81-88, 2013; PubMed: 24001052; DOI: 10.1042/BJ20130796

Experimental method

X-RAY DIFFRACTION (1.9 Å)