4DEN

Structural insightsinto potent, specific anti-HIV property of actinohivin; Crystal structure of actinohivin in complex with alpha(1-2) mannobiose moiety of high-mannose type glycan of gp120

4DEN の概要

• エントリーDOI: 10.2210/pdb4den/pdb
• 関連するPDBエントリー: 3A07
• 関連するBIRD辞書のPRD_ID: PRD_900111
• 分子名称: Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, POTASSIUM ION, ... (4 entities in total)
• 機能のキーワード: anti-hiv lectin, molecular recognition, high-mannose type glycan, antiviral protein
• 由来する生物種: Actinomycete
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13676.68

構造登録者

Hoque, M.M.,Suzuki, K.,Tsunoda, M.,Jiang, J.,Zhang, F.,Takahashi, A.,Naomi, O.,Zhang, X.,Sekiguchi, T.,Tanaka, H.,Omura, S.,Takenaka, A. (登録日: 2012-01-20, 公開日: 2012-11-28, 最終更新日: 2023-11-08)

• 主引用文献: Hoque, M.M.,Suzuki, K.,Tsunoda, M.,Jiang, J.,Zhang, F.,Takahashi, A.,Ohbayashi, N.,Zhang, X.,Tanaka, H.,Omura, S.,Takenaka, A.; Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the alpha(1–2)mannobiose moiety of gp120; Acta Crystallogr.,Sect.D, 68:1671-1679, 2012; PubMed: 23151632; DOI: 10.1107/S0907444912040498

実験手法

X-RAY DIFFRACTION (1.6 Å)