4DCQ

Crystal Structure of the Fab Fragment of 3B5H10, an Antibody-Specific for Extended Polyglutamine Repeats (orthorhombic form)

Summary for 4DCQ

• Entry DOI: 10.2210/pdb4dcq/pdb
• Related: 3S96
• Descriptor: 3B5H10 FAB Light Chain, 3B5H10 FAB Heavy Chain, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: fab fragment, immunoglobulin domain, anti-polyglutamine, polyglutamine repeats, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47223.02

Authors

Peters-Libeu, C.A.,Tran, T.,Finkbeiner, S.,Weisgraber, K. (deposition date: 2012-01-18, release date: 2012-02-22, Last modification date: 2023-09-13)

• Primary citation: Peters-Libeu, C.,Miller, J.,Rutenber, E.,Newhouse, Y.,Krishnan, P.,Cheung, K.,Hatters, D.,Brooks, E.,Widjaja, K.,Tran, T.,Mitra, S.,Arrasate, M.,Mosquera, L.A.,Taylor, D.,Weisgraber, K.H.,Finkbeiner, S.; Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.; J.Mol.Biol., 421:587-600, 2012; PubMed: 22306738; DOI: 10.1016/j.jmb.2012.01.034

Experimental method

X-RAY DIFFRACTION (1.94 Å)