4DC2

Structure of PKC in Complex with a Substrate Peptide from Par-3

Summary for 4DC2

• Entry DOI: 10.2210/pdb4dc2/pdb
• Descriptor: Protein kinase C iota type, Partitioning defective 3 homolog, ADENINE, ... (4 entities in total)
• Functional Keywords: kinase, substrate, cell polarity, par-3, atypical pkc, transferase-transferase substrate complex, transferase/transferase substrate
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm (By similarity): Q62074; Endomembrane system: Q9Z340
• Total number of polymer chains: 2
• Total formula weight: 49039.89

Authors

Shang, Y.,Wang, C.,Yu, J.,Zhang, M. (deposition date: 2012-01-17, release date: 2012-07-11)

• Primary citation: Wang, C.,Shang, Y.,Yu, J.,Zhang, M.; Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKC iota in complex with a substrate peptide from Par-3; Structure, 20:791-801, 2012; PubMed: 22579248; DOI: 10.1016/j.str.2012.02.022

Experimental method

X-RAY DIFFRACTION (2.4 Å)