4DC2

Structure of PKC in Complex with a Substrate Peptide from Par-3

4DC2 の概要

• エントリーDOI: 10.2210/pdb4dc2/pdb
• 分子名称: Protein kinase C iota type, Partitioning defective 3 homolog, ADENINE, ... (4 entities in total)
• 機能のキーワード: kinase, substrate, cell polarity, par-3, atypical pkc, transferase-transferase substrate complex, transferase/transferase substrate
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm (By similarity): Q62074; Endomembrane system: Q9Z340
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 49039.89

構造登録者

Shang, Y.,Wang, C.,Yu, J.,Zhang, M. (登録日: 2012-01-17, 公開日: 2012-07-11)

• 主引用文献: Wang, C.,Shang, Y.,Yu, J.,Zhang, M.; Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKC iota in complex with a substrate peptide from Par-3; Structure, 20:791-801, 2012; PubMed: 22579248; DOI: 10.1016/j.str.2012.02.022

実験手法

X-RAY DIFFRACTION (2.4 Å)