4DAN

Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2-fluoroadenosine

4DAN の概要

• エントリーDOI: 10.2210/pdb4dan/pdb
• 関連するPDBエントリー: 4D8V 4D8X 4D8Y 4D98 4D9H 4DA0 4DA6 4DA7 4DA8 4DAB 4DAE 4DAO 4DAR
• 分子名称: Purine nucleoside phosphorylase deoD-type, 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL (2 entities in total)
• 機能のキーワード: phosphorylase/hydrolase-like, transferase
• 由来する生物種: Bacillus subtilis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55694.74

構造登録者

Giuseppe, P.O.,Martins, N.H.,Meza, A.N.,Murakami, M.T. (登録日: 2012-01-13, 公開日: 2012-09-26, 最終更新日: 2024-02-28)

• 主引用文献: de Giuseppe, P.O.,Martins, N.H.,Meza, A.N.,Dos Santos, C.R.,Pereira, H.D.,Murakami, M.T.; Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases.; Plos One, 7:e44282-e44282, 2012; PubMed: 22957058; DOI: 10.1371/journal.pone.0044282

実験手法

X-RAY DIFFRACTION (2.56 Å)