4DAJ

Structure of the M3 Muscarinic Acetylcholine Receptor

4DAJ の概要

• エントリーDOI: 10.2210/pdb4daj/pdb
• 分子名称: Muscarinic acetylcholine receptor M3, Lysozyme, (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, PHOSPHATE ION (3 entities in total)
• 機能のキーワード: g protein-coupled receptor, muscarinic receptor, acetylcholine receptor, signaling protein, hydrolase
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P08483
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 222480.95

構造登録者

Kruse, A.C.,Hu, J.,Pan, A.C.,Arlow, D.H.,Rosenbaum, D.M.,Rosemond, E.,Green, H.F.,Liu, T.,Chae, P.S.,Dror, R.O.,Shaw, D.E.,Weis, W.I.,Wess, J.,Kobilka, B. (登録日: 2012-01-12, 公開日: 2012-02-22, 最終更新日: 2023-09-13)

• 主引用文献: Kruse, A.C.,Hu, J.,Pan, A.C.,Arlow, D.H.,Rosenbaum, D.M.,Rosemond, E.,Green, H.F.,Liu, T.,Chae, P.S.,Dror, R.O.,Shaw, D.E.,Weis, W.I.,Wess, J.,Kobilka, B.K.; Structure and dynamics of the M3 muscarinic acetylcholine receptor.; Nature, 482:552-556, 2012; PubMed: 22358844; DOI: 10.1038/nature10867

実験手法

X-RAY DIFFRACTION (3.4 Å)