4D9M

Crystal structure of Diaminopropionate ammonia lyase from Escherichia coli in complex with aminoacrylate-PLP azomethine reaction intermediate

4D9M の概要

• エントリーDOI: 10.2210/pdb4d9m/pdb
• 関連するPDBエントリー: 4D9G 4D9I 4D9K 4D9N
• 分子名称: Diaminopropionate ammonia-lyase, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid (3 entities in total)
• 機能のキーワード: fold type ii plp-dependent enzyme, tryptophan synthase beta subunit-like plp-dependent enzymes superfamily, lyase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 87377.24

構造登録者

Bisht, S.,Rajaram, V.,Bharath, S.R.,Murthy, M.R.N. (登録日: 2012-01-11, 公開日: 2012-04-25, 最終更新日: 2023-11-08)

• 主引用文献: Bisht, S.,Rajaram, V.,Bharath, S.R.,Kalyani, J.N.,Khan, F.,Rao, A.N.,Savithri, H.S.,Murthy, M.R.N.; Crystal Structure of Escherichia coli Diaminopropionate Ammonia-lyase Reveals Mechanism of Enzyme Activation and Catalysis; J.Biol.Chem., 287:20369-20381, 2012; PubMed: 22505717; DOI: 10.1074/jbc.M112.351809

実験手法

X-RAY DIFFRACTION (2.5 Å)